Cook has run Apple twice before: first for two months in 2004 while Jobs battled pancreatic cancer, and once again for five-and-a-half months in 2009 while Jobs received a liver transplant.
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.The first time Cook was in charge, things went so well that Apple promoted him from executive vice president to chief operating officer in 2005. Cook has since become Apple's top-paid executive, with a salary of $900,000 for the current fiscal year. (Jobs limits his salary to $1.)
Story: Apple's Jobs takes medical leave of absence